Transdermal Estrogen Replacement Therapy and Vasomotor Response.
نویسندگان
چکیده
منابع مشابه
Transdermal estrogen replacement therapy decreases sympathetic activity in postmenopausal women.
BACKGROUND Menopause heralds a dramatic increase in incident hypertension, suggesting a protective effect of estrogen on blood pressure (BP). In female rats, estrogen has been shown to decrease sympathetic nerve discharge (SND) and BP. SND, however, has not been recorded during estrogen replacement therapy (ERT) in humans. Methods and Results-In 12 normotensive postmenopausal women, we conducte...
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To study the mechanisms of low density lipoprotein (LDL) cholesterol lowering by peroral and transdermal estrogen replacement therapy (ERT), 79 hysterectomized postmenopausal women aged 48 to 62 years were randomized in a double-blind double-dummy trial to receive either peroral estradiol valerate (2 mg/d) or transdermal estradiol gel (1 mg/d) for 6 months. Plasma LDL cholesterol decreased from...
متن کاملDifferential effects of oral and transdermal estrogen replacement therapy on endothelial function in postmenopausal women.
BACKGROUND We determined whether the vascular effects of estradiol depend on the route of administration by comparing the effects of oral estradiol and transdermal placebo, transdermal estradiol and oral placebo, and transdermal placebo and oral placebo on in vivo endothelial function in 27 postmenopausal women. METHODS AND RESULTS Endothelial function was assessed from blood flow responses t...
متن کاملTransdermal testosterone replacement therapy in men
Androgen deficiency syndrome in men is a frequently diagnosed condition associated with clinical symptoms including fatigue, decreased libido, erectile dysfunction, and metabolic syndrome. Serum testosterone concentrations decline steadily with age. The prevalence of androgen deficiency syndrome in men varies depending on the age group, known and unknown comorbidities, and the respective study ...
متن کاملDifferential effects of oral versus transdermal estrogen replacement therapy on C-reactive protein in postmenopausal women.
OBJECTIVES We investigated whether the route of estrogen replacement therapy (ET) is the major determinant of C-reactive protein (CRP) in postmenopausal women. BACKGROUND Recent studies demonstrated that oral ET causes a sustained increase in CRP, implicating a proinflammatory effect. Because CRP is synthesized in the liver, we hypothesized that estrogen-induced CRP elevation is related to fi...
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ژورنال
عنوان ژورنال: Japanese Heart Journal
سال: 2001
ISSN: 0021-4868,1348-673X
DOI: 10.1536/jhj.42.307